Via a catheter, ALZET^R Osmotic Pumps can deliver substances into the venous or arterial circulation, into the brain, or into any organ lumen, or solid tissue. DURECT Corporation offers a range of specialized catheters, compatible with ALZET pumps, to enable targeted delivery to a variety of sites.

Catheter applications with ALZET Osmotic Pumps

Common Routes of Administration Requiring Use of a Catheter

• Direct delivery of test agents pecisely into any target tissue or organ
• Delay administration of test agents to allow for a surgical recovery period
• Infuse for a short period using a longer duration pump
• Create a time-patterned delivery of an agent

Note: No catheter is necessary when systemic delivery is desired. This is accomplished by subcutaneous or intraperitoneal implantation of an ALZET pump without a catheter.

• Articular cavity
• Blood vessels
• Bone
• Brain (solid tissue)
• Brain (ventricles)
• Ear
• Eye
• Muscle
• Nerves
• Spinal cord
• Stomach
• Tumors

Specifications

Features

• Sterile
• Medical grade
• Pre-cut to 15 cm lengths
• Individually packaged
• Ready to use
• Fit all pump models

Rat Jugular Catheter

Order No.: 0007710

Catheter Material: Silicon

Specifications:

15.24 cm (6") of silicon catheter (0.94 OD; 0.51 mm ID) with a Dacron suture patch and ALZET connection (1.19 mm OD; 0.61 mm ID)

Optimum Animal Size:

250+ grams (for <250 gram rats, cut tip to size for proper placement)

Features & Benefits:

• Dacron patch facilitates anchoring to tissue
• Silicon material is very flexible and less traumatic to vessels
• Bevel tip if desired for easier insertion into vessels
• ETO sterilized

Rat Femoral Catheter

Order No.: 0007720

Catheter Material: Polyurethane (PU)

Specifications:

20.32 cm (8") of Polyurethane catheter (1.02 mm OD; 0.61 mm ID)

Optimum Animal Size:

Up to 300+ grams (for <175 gram rats, cut tip to size for proper placement)

Features & Benefits:

• Retention beads at 3.81, 5.08, and 7.62 cm from the tip facilitate anchoring to tissue
• Medical grade polyurethane softens at body temperature
• Fits directly to pump (no step-up needed)

Rat Femoral Catheter (Tapered)

Order No.: 0007730

Catheter Material: Opaque Polyurethane

Specifications:

20.32 cm (8") of tapered radio-opaque polyurethane (1.40 mm to 0.99 mm OD; 0.61 mm constant ID)

Optimum Animal Size:

Up to 300+ grams (for <175 gram rats, cut tip to size for proper placement)

Features & Benefits:

• Retention beads at 3.81, 5.08, and 7.62 cm from the tip facilitate anchoring to tissue
• Medical grade, tapered polyurethane minimizes kinking
• Radio-opaque material and smooth surface minimize clotting
• Lumen maintains consistent ID, so that the catheter can be shortened without compromising its tight fit onto pump

Rat Intrathecal Catheter

Order No.: 0007740

Catheter Material: Polyurethane (PU)

Specifications:

10 cm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 12.7 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID) with stainless steel stylet

Optimum Animal Size:

Up to 300+ grams (cut to desired length for proper placement)

Features & Benefits:

• Teflon coated stylet slides smoothly out of catheter
• Protected tubing junction minimizes kinking at exit point from intrathecal space

Mouse Jugular Catheter

Order No.: 0007700

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 63.5 mm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID)

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

• Retention beads at 13 and 38 mm from the tip facilitate anchoring to tissue
• Marked at 9 and 11 mm to simplify adaptation for <25 and 25-30 gram animals respectively

*All specialized catheters are supplied sterile (ETO sterilized)