Item Number: 0008670 Comes as: 3 gram tube
Loctite 454 is an instant adhesive gel for use with ALZETR Brain Infusion Kits and other brain infusion cannulae. It offers a convenient alternative to cranioplastic or dental cements. A very thin layer on the base of the pedestal adheres the cannula to the skull. Researchers have found it to be ideal for use in mice and other small animals when using short pedestal cannulae.
Product Description & Applications
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No mix, instant adhesive gel for use with ALZET R Brain Infusion Kits and other brain infusion cannulae
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One 3 gram tube is enough for 10 brain infusion cannulae implantations
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A convenient alternative to cranioplastic / dental cement
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A very thin layer on the base of the pedestal adheres the cannula to the dry skull
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Ideal for use in mice and other small animals when using short pedestal cannulae
Advantages of Cyanoacrylate Gel Over Dental Cement
Significant time savings for the researcher
Significant animal welfare benefit *
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Less stress to the experimental animal
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Reduced time under anesthesia
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Less adhesive material needed, thereby less overall implant size and weight on the animals
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Easier to close the skin over the cannula
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Minimal heat generated during curing
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Less trauma to animals since fewer (or no) screws required to stabilize the cannula
References
* Criado, A. et al . Use of cyanoacrylate gel as a substitute for dental cement in intracerebroventricular cannulations in rats. Contemporary Topics 2003; 42(3):13-16. (Review of Study) |